Dementia, 4th Edition

Summary:
Winner of the BMA 2011 book awards: psychiatry category
Winner of the Australian Journal of Ageing book of the year award

This definitive work on dementia and related disorders has been fully updated and revised to reflect recent advances in this fast-moving field.
The incidence of dementia continues to rise as the population of the world ages, and the condition represents one of the most significant challenges facing societies and health professionals in the next half-century. In this, the most comprehensive single volume work available on the subject, the editors have met this challenge by assembling a team of the world's leading experts on all aspects of the condition, from history, epidemiology and social aspects to the latest neurobiological research and advanced therapeutic strategies.

The new edition includes:

• The definitive work on the subject of dementia
• Truly international chapter authorship, representing the cream of the world's dementia researchers and clinicians
• Fully revised and updated, reflecting the nature of this fast moving field
• Essential reading for old age psychiatrists and anyone whose work involves patients with dementia

Table of Contents:
Part I – Dementia: General Aspects
Introduction
1. Dementia: historical overview
2. The lived experience of dementia
3. Prevalence and incidence of dementia
Diagnosis and assessment
4. Criteria for the diagnosis of dementia
5. Assessment of the patient with apparent dementia
6. Screening and assessment instruments for the detection and measurement of cognitive impairment
7. Neuropsychological assessment of dementia
8. Neuropsychiatric aspects of dementia
9. Measurement of neuropsychiatric symptoms, behavioural disturbance and quality of life
10. Cross-cultural issues in the assessment of cognitive impairment
11. Structural brain imaging
12. Functional brain imaging and connectivity in dementia
13. Molecular brain imaging in dementia
14. The neurophysiology of dementia
15. Family carers of people with dementia
16. One caregiver’s view
17. Dementia care in the community: challenges for primary health and social care
18. Managing co-morbidities and general hospital admissions for people with dementia
19. The role of nursing in the management of dementia
20. Social work and care/case management in dementia
21. Occupational therapy in dementia care
22. The role of the speech and language therapist in the assessment and management of the person with dementia
23. The role of physiotherapy in the management of dementia
24. Therapeutic effects of music in people with dementia
25. Non-pharmacological therapies to manage behavioural and psychological symptoms of dementia: what works and what doesn't
26. A predominantly psychosocial approach to behaviour problems in dementia: treating causality
27. Drug treatments for the behavioural and psychiatric symptoms of dementia
28. Psychological approaches for the practical management of cognitive impairment in dementia
29. Sexuality and dementia
30. Residential care for people with dementia
31. Design and dementia
32. Legal issues and dementia
33. Driving and dementia
34. Quality of life in dementia: conceptual and practical issues
35. Ethical issues and dementia
36. End-of-life decisions and dementia
37. Care and management of the patient with advanced dementia
38. Alzheimer associations and societies
39. Health economic aspects of dementia
40. The global challenge of dementia: what can be done
41. Development of a national strategy for dementia: dementia and policy in the UK
42. The pharmaceutical industry and dementia: how can clinicians, researchers and industry work together ethically for the betterment of people with dementia and their families?
Part II Mild cognitive impairment
43. Mild cognitive impairment: a historical perspective
44. Clinical characterization of mild cognitive impairment
45. Managing the patient with mild cognitive impairment
Part III Alzheimer’s disease
46. What is Alzheimer’s disease?
47. Risk factors for Alzheimer’s disease
48. The natural history of Alzheimer’s disease
49. The neuropathology of Alzheimer’s disease
50. Neurochemistry of Alzheimer's disease
51. The central role of Aß amyloid in the pathogenesis of Alzheimer's disease
52. Genetics of Alzheimer's disease
53. Blood and cerebrospinal fluid biomarkers for Alzheimer’s disease
54. Established treatments for Alzheimer's disease: cholinesterase inhibitors and memantine
55. Drug treatments in development for Alzheimer’s disease
56. Stem cell therapies for Alzheimer’s disease and other dementias
57. Vitamins and complementary therapies used to treat Alzheimer’s disease
58. Prevention of Alzheimer’s disease
59. Trial designs
Part IV The overlap and interaction between Alzheimer’s disease and cerebrovascular disease
60. Vascular factors and Alzheimer’s disease
Part V Cerebrovascular disease and cognitive impairment
61. What is vascular cognitive impairment?
62. The neuropathology of vascular dementia
63. Therapeutic strategies for vascular dementia and vascular cognitive disorders
Part VI Dementia with Lewy bodies and Parkinson’s disease
64. Dementia with Lewy bodies: a clinical and historical overview
65. Pathology of dementia with Lewy bodies
66. The treatment of dementia with Lewy bodies
67. Cognitive impairment and dementia in Parkinson’s disease
Part VII Focal dementias and related issues
68. Frontotemporal dementia
69. Pick's disease: its relationship to progressive aphasia, semantic dementia and frontotemporal dementia
70. The genetics and molecular pathology of frontotemporal lobar degeneration
71. Semantic dementia
72. Primary progressive aphasia and posterior cortical atrophy
73. The cerebellum and cognitive impairment
Part VIII Other dementias and neuropsychiatric disorders associated with cognitive impairments
74. Depression with cognitive impairment
75. Schizophrenia, cognitive impairment and dementia
76. Dementia in intellectual disabilities
77. Alcohol-related dementia and Wernicke-Korsakoff syndrome
78. Huntingdon’s disease
79. Creutzfeldt-Jakob disease and other prion diseases
80. Uncommon forms of dementia

About the Author(s):
David Ames BA MD FRCPsych FRANZCP
Professor of Ageing and Health
National Ageing Research Institute
University of Melbourne, Parkville, Victoria, Australia

Alistair Burns MPhil MD FRCP FRCPsych
Professor of Old Age Psychiatry
University of Manchester, Manchester, UK

John O'Brien MA DM, FRCPsych
Professor of Old Age Psychiatry
Institute for Ageing and Health, Newcastle University
Newcastle upon Tyne, UK

Contributors:
Dag Aarsland MD PhD Psychiatric Clinic, Stavanger University Hospital, Stavanger, Norway George S Alexopoulos MD Weill Cornell Medical College, White Plains, NY, USA Osvaldo P Almeida Western Australian Centre for Health and Ageing, School of Psychiatry and Clinical Neurosciences and Centre for Medical Research, University of Western Australia; Department of Psychiatry, Royal Perth Hospital, Perth, Australia June Andrews Iris Murdoch Building, University of Stirling, Stirling, UK Sylvaine Artero PHD INSERM U888, Nervous System Pathologies: Epidemiological and Clinical Research, La Colombière Hospital, Montpellier, France Clive Ballard Wolfson Centre for Age Related Diseases, Guy’s Campus, London, UK Sube Banerjee Professor of Mental Health and Ageing, The Institute of Psych

Readership:
Psychiatrists (9600 in the England) especially those specialising in in old age psychiatry (1300 of the 9600) and general psychiatry (600 of the 9600). Geriatricians (3000 in England). Neurologists (1

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